Bigpicc: a graph-based approach to identifying carcinogenic gene combinations from mutation data

Abstract Genome data from cancer patients represents relationships between the presence of a gene mutation and cancer occurrence in a patient. Different types of cancer in human are thought to be caused by combinations of two to nine gene mutations. Identifying these combinations through traditional...

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Bibliographic Details
Main Authors: Vladyslav Oles, Sajal Dash, Ramu Anandakrishnan
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-025-06043-1
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