One‐Pot Gram‐Scale Synthesis of Cynandione A and Detailed Mechanistic Insights into its Regioselectivity

One‐Pot Gram‐Scale Synthesis of Cynandione A and Detailed Mechanistic Insights into its Regioselectivity

Abstract Cynandione A, a natural biaryl product with a bis‐acetophenone structure isolated from Cynanchi wilfordii Radix, has garnered considerable attention because of its diverse biological activities, including anti‐inflammatory, neuroprotective, antioxidant, and adipogenic effects. However, the...

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Bibliographic Details
Main Authors: Jun Sung Kang, Jin Yi Jung, Chan Jae Cho, Seoungwoo Kang, Prof. Yeonjoon Kim, Prof. Jae Hyun Kim
Format: Article
Language:English
Published: Wiley-VCH 2025-08-01
Series:ChemistryOpen
Subjects:
Biaryls
Density functional calculations
Quinones
Regioselectivity
Total synthesis
Online Access:https://doi.org/10.1002/open.202500001
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https://doi.org/10.1002/open.202500001

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