Mechanism of interaction between TTR tetramer and Aβ42 oligomers: Dependence on the Aβ42 oligomeric size and morphology

β-amyloid (Aβ) deposits are the leading cause of Alzheimer's disease. Many studies have confirmed that transthyretin (TTR) inhibits the cytotoxicity of Aβ oligomers (AβOs) with various species (oligomers and protofibrils, but not monomers) through their interactions. Here, we investigated the m...

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Bibliographic Details
Main Authors: Jinfei Mei, Wenqi Gao, Yvning Guan, Sajjad Ahmad, Fahad Nouman Muhammad, Hongqi Ai
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-04-01
Series:ChemPhysMater
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Online Access:http://www.sciencedirect.com/science/article/pii/S2772571525000099
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