Seronegative Sicca Syndrome: Diagnostic Considerations and Management Strategies

Seronegative Sicca Syndrome: Diagnostic Considerations and Management Strategies

Seronegative sicca syndrome encompasses patients who present with xerostomia and/or keratoconjunctivitis sicca but lack anti-SSA/SSB antibodies and do not fulfill current classification criteria for primary Sjögren’s syndrome (pSS). Despite symptom overlap with pSS, these individuals remain diagnost...

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Main Authors: Yordanka M. Basheva-Kraeva, Krasimir I. Kraev, Petar A. Uchikov, Maria I. Kraeva, Bozhidar K. Hristov, Nina St. Stoyanova, Vesela T. Mitkova-Hristova, Borislav Ivanov, Stanislav S. Karamitev, Nina Koleva, Aleksandar Marinkov, Veselin A. Vassilev
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Life
Subjects:
seronegative sicca syndrome
primary Sjögren’s syndrome
autoimmune exocrinopathy
Online Access:https://www.mdpi.com/2075-1729/15/6/966
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