Alterations of the microenvironment of hepatocellular carcinoma in different unfolded protein response activity states

Abstract Background The unfolded protein response (UPR) is an adaptive and cytoprotective sensing-signaling network. Numerous studies have indicated the crucial role of UPR in the anti-tumor drug resistance and the modification of tumor microenvironment (TME). The aim of this study is to analyze the...

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Bibliographic Details
Main Authors: Yao Wang, Xiao Fei Zhu, Wan Jian Gu, Gui Hong Zhang
Format: Article
Language:English
Published: Springer 2025-03-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-025-02164-4
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