LSD1+8a is an RNA biomarker of neuroendocrine prostate cancer

LSD1+8a is an RNA biomarker of neuroendocrine prostate cancer

Background: Lysine-specific demethylase 1 (LSD1) is a histone demethylase and regulator of differentiation, including in cancer. A neuronal-specific isoform of LSD1—LSD1+8a—has been shown to play a key role in promoting neuronal differentiation in the developing brain. We previously determined that...

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Main Authors: Anbarasu Kumaraswamy, Rahul Mannan, Olivia A. Swaim, Eva Rodansky, Xiao-Ming Wang, Aaron Udager, Rohit Mehra, Hui Li, Colm Morrissey, Eva Corey, Michael C. Haffner, Peter S. Nelson, Arul M. Chinnaiyan, Joel A. Yates, Joshi J. Alumkal
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
LSD1+8a
Neuroendocrine Prostate Cancer
RNA Biomarker
RNA In Situ Hybridization
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558625000302
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