Connection between oral health and chronic diseases

Abstract Chronic diseases have emerged as a paramount global health burden, accounting for 74% of global mortality and causing substantial economic losses. The oral cavity serves as a critical indicator of overall health and is inextricably linked to chronic disorders. Neglecting oral health can exa...

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Main Authors: Di Fu, Xingyue Shu, Ge Zhou, Mengzhen Ji, Ga Liao, Ling Zou
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:MedComm
Subjects:
Online Access:https://doi.org/10.1002/mco2.70052
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author Di Fu
Xingyue Shu
Ge Zhou
Mengzhen Ji
Ga Liao
Ling Zou
author_facet Di Fu
Xingyue Shu
Ge Zhou
Mengzhen Ji
Ga Liao
Ling Zou
author_sort Di Fu
collection DOAJ
description Abstract Chronic diseases have emerged as a paramount global health burden, accounting for 74% of global mortality and causing substantial economic losses. The oral cavity serves as a critical indicator of overall health and is inextricably linked to chronic disorders. Neglecting oral health can exacerbate localized pathologies and accelerate the progression of chronic conditions, whereas effective management has the potential to reduce their incidence and mortality. Nevertheless, limited resources and lack of awareness often impede timely dental intervention, delaying optimal therapeutic measures. This review provides a comprehensive analysis of the impact of prevalent chronic diseases—such as diabetes mellitus, rheumatoid arthritis, cardiovascular disorders, and chronic respiratory diseases—on oral health, along with an exploration of how changes in oral health affect these chronic conditions through both deterioration and intervention mechanisms. Additionally, novel insights into the underlying pathophysiological mechanisms governing these relationships are presented. By synthesizing these advancements, this review aims to illuminate the complex interrelationship between oral health and chronic diseases while emphasizing the urgent need for greater collaboration between dental practitioners and general healthcare providers to improve overall health outcomes.
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spelling doaj-art-c2470682d53949f4bd7eaad6bf944cd62025-01-20T01:45:44ZengWileyMedComm2688-26632025-01-0161n/an/a10.1002/mco2.70052Connection between oral health and chronic diseasesDi Fu0Xingyue Shu1Ge Zhou2Mengzhen Ji3Ga Liao4Ling Zou5State Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases Sichuan University Chengdu Sichuan ChinaState Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases Sichuan University Chengdu Sichuan ChinaState Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases Sichuan University Chengdu Sichuan ChinaState Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases Sichuan University Chengdu Sichuan ChinaState Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases Sichuan University Chengdu Sichuan ChinaState Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Department of Conservative Dentistry and Endodontics, West China Hospital of Stomatology Sichuan University Chengdu Sichuan ChinaAbstract Chronic diseases have emerged as a paramount global health burden, accounting for 74% of global mortality and causing substantial economic losses. The oral cavity serves as a critical indicator of overall health and is inextricably linked to chronic disorders. Neglecting oral health can exacerbate localized pathologies and accelerate the progression of chronic conditions, whereas effective management has the potential to reduce their incidence and mortality. Nevertheless, limited resources and lack of awareness often impede timely dental intervention, delaying optimal therapeutic measures. This review provides a comprehensive analysis of the impact of prevalent chronic diseases—such as diabetes mellitus, rheumatoid arthritis, cardiovascular disorders, and chronic respiratory diseases—on oral health, along with an exploration of how changes in oral health affect these chronic conditions through both deterioration and intervention mechanisms. Additionally, novel insights into the underlying pathophysiological mechanisms governing these relationships are presented. By synthesizing these advancements, this review aims to illuminate the complex interrelationship between oral health and chronic diseases while emphasizing the urgent need for greater collaboration between dental practitioners and general healthcare providers to improve overall health outcomes.https://doi.org/10.1002/mco2.70052cardiovascular diseaseschronic diseaseschronic respiratory diseasesdiabetesoral healthrheumatoid arthritis
spellingShingle Di Fu
Xingyue Shu
Ge Zhou
Mengzhen Ji
Ga Liao
Ling Zou
Connection between oral health and chronic diseases
MedComm
cardiovascular diseases
chronic diseases
chronic respiratory diseases
diabetes
oral health
rheumatoid arthritis
title Connection between oral health and chronic diseases
title_full Connection between oral health and chronic diseases
title_fullStr Connection between oral health and chronic diseases
title_full_unstemmed Connection between oral health and chronic diseases
title_short Connection between oral health and chronic diseases
title_sort connection between oral health and chronic diseases
topic cardiovascular diseases
chronic diseases
chronic respiratory diseases
diabetes
oral health
rheumatoid arthritis
url https://doi.org/10.1002/mco2.70052
work_keys_str_mv AT difu connectionbetweenoralhealthandchronicdiseases
AT xingyueshu connectionbetweenoralhealthandchronicdiseases
AT gezhou connectionbetweenoralhealthandchronicdiseases
AT mengzhenji connectionbetweenoralhealthandchronicdiseases
AT galiao connectionbetweenoralhealthandchronicdiseases
AT lingzou connectionbetweenoralhealthandchronicdiseases