Ginger extract inhibits c-MET activation and suppresses osteosarcoma in vitro and in vivo

Ginger extract inhibits c-MET activation and suppresses osteosarcoma in vitro and in vivo

Abstract Background Osteosarcoma (OS) as an invasive and lethal malignancy showing a low 5-year survival rate requires novel therapeutic targets and their suppressors to improve prevention and treatment strategies. Methods Our research served to clarify the therapeutic potential of ginger extract an...

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Main Authors: Ruoping Yanzhang, Mingyang Yan, Zhaojie Yang, Huijun Zhang, Yin Yu, Xiangping Li, Ruifang Shen, Xiao Chu, Siyuan Han, Ziliang Zhang, Junyan Teng, Hao Li, Tao Li, Guoguo Jin, Zhiping Guo
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Cancer Cell International
Subjects:
Ginger extract
c-MET
Osteosarcoma
PDX model
Online Access:https://doi.org/10.1186/s12935-025-03759-1
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https://doi.org/10.1186/s12935-025-03759-1

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