Principal component analysis of the Serological response to Plasmodium Falciparum using a Multiplex bead-based assay in Nigeria

Principal component analysis of the Serological response to Plasmodium Falciparum using a Multiplex bead-based assay in Nigeria

Abstract Characterization of serological responses to Plasmodium falciparum (Pf) is of interest to understand disease burden and transmission dynamics; however, their interpretation is challenging. Dried blood spots from 30,815 participants aged 6 months to 15 years from the 2018 Nigeria HIV/AIDS In...

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Main Authors: Jonathan S. Schultz, Mary Okoli, Scott Lee, Colleen M. Leonard, Dean Sayre, Charles M. Heilig, Perpetua Uhomoibhi, Abiodun Ogunniyi, Nnaemeka Ndodo, Nwando Mba, Ado G. Abubakar, Oluwaseun Akinmulero, Ayuba B. Dawurung, McPaul Okoye, Nnaemeka C. Iriemenam, Mateusz Plucinski, Laura Steinhardt, Eric Rogier, Chickwe Ihekweazu
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
Plasmodium Falciparum
Nigeria
Serology
Multiplex bead-based assay (MBA)
Principal component analysis (PCA)
Online Access:https://doi.org/10.1038/s41598-024-74236-4
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https://doi.org/10.1038/s41598-024-74236-4

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