异氟醚通过醛糖还原酶改善线粒体功能保护脑缺血/再灌注损伤

异氟醚通过醛糖还原酶改善线粒体功能保护脑缺血/再灌注损伤

目的探讨异氟醚（ISO）对脑缺血/再灌注（IR）小鼠线粒体功能的影响及其可能机制。方法醛糖还原酶（<italic>AR</italic>）基因敲除的小鼠（<italic>AR</italic><sup>-/-</sup>）及对照野生型小鼠（Wild-type，WT）随机分为WT-S组、WT-IR组、WT-IR+ISO组、<italic>AR</italic><sup>-/-</sup>+S组、<italic>AR</italic><sup>...

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Bibliographic Details
Main Authors: 蒋雯, 李杰, 黄燕, 孙景波, 邓敏贞, 蔡粤芳, Sookja Kim Chung, 程骁
Format: Article
Language:zho
Published: Editorial Office of Journal of Sun Yat-sen University 2021-09-01
Series:Zhongshan Daxue xuebao. Yixue kexue ban
Subjects:
异氟醚
脑缺血/再灌注损伤
醛糖还原酶
线粒体功能
Online Access:http://xuebaoyx.sysu.edu.cn/zh/article/doi/10.13471/j.cnki.j.sun.yat-sen.univ(med.sci).2021.0510/
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http://xuebaoyx.sysu.edu.cn/zh/article/doi/10.13471/j.cnki.j.sun.yat-sen.univ(med.sci).2021.0510/

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