The Src family kinase inhibitor drug Dasatinib and glucocorticoids display synergistic activity against tongue squamous cell carcinoma and reduce MET kinase activity

Abstract Background Tongue squamous cell carcinoma (TSCC) is an aggressive cancer associated with a poor prognosis and limited treatment options, necessitating new drug targets to improve therapeutic outcomes. Our current work studies protein tyrosine kinases as well-known targets for successful can...

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Bibliographic Details
Main Authors: Ali N. A. Hmedat, Jessica Doondeea, Daniel Ebner, Stephan M. Feller, Marc Lewitzky
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Cell Communication and Signaling
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Online Access:https://doi.org/10.1186/s12964-025-02129-8
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