Combination of spatial transcriptomics analysis and retrospective study reveals liver infection of SARS-COV-2 is associated with clinical outcomes of COVID-19Research in context

Combination of spatial transcriptomics analysis and retrospective study reveals liver infection of SARS-COV-2 is associated with clinical outcomes of COVID-19Research in context

Summary: Background: Liver involvement is a common complication of coronavirus disease 2019 (COVID-19), especially in hospitalized patients. However, the underlying mechanisms involved are not fully understood. Methods: Immunohistochemistry (IHC) staining of SARS-CoV-2 spike (S) and nucleocapsid (N...

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Main Authors: Shiqi Chen, Yi Zhang, Asha Ashuo, Shu Song, Lunzhi Yuan, Weixia Wang, Cong Wang, Zunguo Du, Yangtao Wu, Dan Tan, Chenlu Huang, Jingna Chen, Yaming Li, Jinjin Bai, Huilin Guo, Zehong Huang, Yi Guan, Ningshao Xia, Zhenghong Yuan, Jiming Zhang, Quan Yuan, Zhong Fang
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:EBioMedicine
Subjects:
SARS-COV-2
COVID-19
Liver
Spatial transcriptome
ALB
Online Access:http://www.sciencedirect.com/science/article/pii/S235239642400553X
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