Remodeling of the chromatin landscape in peripheral blood cells in patients with severe Delta COVID-19

Remodeling of the chromatin landscape in peripheral blood cells in patients with severe Delta COVID-19

COVID-19 is characterized by systemic pro-inflammatory shifts with the development of serious alterations in the functioning of the immune system. Investigations of the gene expression changes accompanying the infection state provide insight into the molecular and cellular processes depending on the...

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Main Authors: Vasiliy E. Akimov, Dmitriy I. Tychinin, Olga A. Antonova, Abusaid M. Shaymardanov, Maria D. Voronina, Kseniia A. Deinichenko, Oleg D. Fateev, Vladimir S. Yudin, Sergey M. Yudin, Vladimir E. Mukhin, Svetlana V. Romanova, Aleksandra I. Nekrasova, Anastasia S. Zhdanova, Anastasia V. Tsypkina, Ivan S. Vladimirov, Antonida V. Makhotenko, Anton A. Keskinov, Sergey A. Kraevoy, Ekaterina A. Snigir, Dmitry V. Svetlichnyy, Veronika I. Skvortsova
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Immunology
Subjects:
scATAC-seq
single cell
COVID-19
transcriptional regulatory network
PBMC (peripheral blood mononuclear cells)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1415317/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1415317/full

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