K-ras mutation predictive significance in platinum based chemotherapeutic protocols in patients with advanced non-small cell lung cancer

K-ras mutation predictive significance in platinum based chemotherapeutic protocols in patients with advanced non-small cell lung cancer

Beckground/Aim. K-ras oncogene is mutated in about 20% of lung cancer. The purpose of this study was to investigate the predictive significance for therapeutic response of K-ras mutations in advanced non-small cell lung cancer (NSCLC) patients. Methods. Bronchial aspirate samples were assessed prior...

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Bibliographic Details
Main Authors: Cvetković Gordana, Plavec Goran, Tomić Ilija, Ilić Vesna, Magić Zvonko, Tatomirović Željka, Novković Dobrivoje, Milić Rade, Karličić Vukojica
Format: Article
Language:English
Published: Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade 2009-01-01
Series:Vojnosanitetski Pregled
Subjects:
carcinoma, non-small-cell lung
genes, ras
antineoplastic combined chemotherapy protocols
platinum compounds
prognosis
Online Access:http://www.doiserbia.nb.rs/img/doi/0042-8450/2009/0042-84500902149C.pdf
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