Combining single-cell ATAC and RNA sequencing for supervised cell annotation

Combining single-cell ATAC and RNA sequencing for supervised cell annotation

Abstract Motivation Single-cell analysis offers insights into cellular heterogeneity and individual cell function. Cell type annotation is the first and critical step for performing such an analysis. Current methods mostly utilize single-cell RNA sequencing data. Several studies demonstrated improve...

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Bibliographic Details
Main Authors: Jaidip Gill, Abhijit Dasgupta, Brychan Manry, Natasha Markuzon
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Bioinformatics
Subjects:
RNA
ATAC
Machine learning
Cell annotation
Single-cell sequencing
Online Access:https://doi.org/10.1186/s12859-025-06084-6
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https://doi.org/10.1186/s12859-025-06084-6

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