Study on Interaction of Cationic Porphyrazine with Synthetic Polynucleotides
Interactions of cationic tetrakis (N, N′, N″, N‴- tetramethyltetra-3, 4-pyridinoporphyrazinatozinc (II) (Zn (tmtppa)) with synthetic polynucleotides, poly (G-C) and poly (A-T), and calf thymus DNA have been characterized in 7.5 mM phosphate buffer of pH 7.2 by UV-Vis absorption and fluorescence spec...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Analytical Cellular Pathology |
| Online Access: | http://dx.doi.org/10.3233/ACP-140086 |
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| author | Hamid Dezhampanah Soghra Fyzolahjani |
| author_facet | Hamid Dezhampanah Soghra Fyzolahjani |
| author_sort | Hamid Dezhampanah |
| collection | DOAJ |
| description | Interactions of cationic tetrakis (N, N′, N″, N‴- tetramethyltetra-3, 4-pyridinoporphyrazinatozinc (II) (Zn (tmtppa)) with synthetic polynucleotides, poly (G-C) and poly (A-T), and calf thymus DNA have been characterized in 7.5 mM phosphate buffer of pH 7.2 by UV-Vis absorption and fluorescence spectroscopy. The appearance of hypochromicity more than 30% in UV-Vis spectra of porphyrazine due to interaction of both poly (G-C) and poly (A-T) indicates interaction similar to that of porphyrazine with DNA. |
| format | Article |
| id | doaj-art-c11313ebaac34d6a894fa6a0d631b58e |
| institution | Kabale University |
| issn | 2210-7177 2210-7185 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Analytical Cellular Pathology |
| spelling | doaj-art-c11313ebaac34d6a894fa6a0d631b58e2025-02-03T06:45:17ZengWileyAnalytical Cellular Pathology2210-71772210-71852013-01-01365-612513210.3233/ACP-140086Study on Interaction of Cationic Porphyrazine with Synthetic PolynucleotidesHamid Dezhampanah0Soghra Fyzolahjani1Laboratory of Physical Chemistry, Faculty of Science, Department of Chemistry, University of Guilan, Rasht, IranLaboratory of Physical Chemistry, Faculty of Science, Department of Chemistry, University of Guilan, Rasht, IranInteractions of cationic tetrakis (N, N′, N″, N‴- tetramethyltetra-3, 4-pyridinoporphyrazinatozinc (II) (Zn (tmtppa)) with synthetic polynucleotides, poly (G-C) and poly (A-T), and calf thymus DNA have been characterized in 7.5 mM phosphate buffer of pH 7.2 by UV-Vis absorption and fluorescence spectroscopy. The appearance of hypochromicity more than 30% in UV-Vis spectra of porphyrazine due to interaction of both poly (G-C) and poly (A-T) indicates interaction similar to that of porphyrazine with DNA.http://dx.doi.org/10.3233/ACP-140086 |
| spellingShingle | Hamid Dezhampanah Soghra Fyzolahjani Study on Interaction of Cationic Porphyrazine with Synthetic Polynucleotides Analytical Cellular Pathology |
| title | Study on Interaction of Cationic Porphyrazine with Synthetic Polynucleotides |
| title_full | Study on Interaction of Cationic Porphyrazine with Synthetic Polynucleotides |
| title_fullStr | Study on Interaction of Cationic Porphyrazine with Synthetic Polynucleotides |
| title_full_unstemmed | Study on Interaction of Cationic Porphyrazine with Synthetic Polynucleotides |
| title_short | Study on Interaction of Cationic Porphyrazine with Synthetic Polynucleotides |
| title_sort | study on interaction of cationic porphyrazine with synthetic polynucleotides |
| url | http://dx.doi.org/10.3233/ACP-140086 |
| work_keys_str_mv | AT hamiddezhampanah studyoninteractionofcationicporphyrazinewithsyntheticpolynucleotides AT soghrafyzolahjani studyoninteractionofcationicporphyrazinewithsyntheticpolynucleotides |