Enhancing tumor penetration: GSH-sensitive paclitaxel liposomes modified with Dermaseptin-PP

Enhancing tumor penetration: GSH-sensitive paclitaxel liposomes modified with Dermaseptin-PP

The dense structure of solid tumor tissues and the selective permeability of cell membranes impede the effective penetration of chemotherapeutic agent-loaded liposomes into tumors and their subsequent uptake by cells. Dermaseptin-PP, a cationic antimicrobial peptide, has demonstrated the ability to...

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Bibliographic Details
Main Authors: Ziyi Dong, Qin Zhang, Qing Zhang, Wenjun Hu, Liwen Yan, Fengqi Peng, Zucheng Hu, Jakkree Tangthianchaichana, Yueying Zhao, Shouying Du, Yang Lu
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Materials & Design
Subjects:
Cancer
Cationic antimicrobial peptides
Membrane-breaking
Liposomes
Combination therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S0264127524006981
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