Management of intraocular pressure and inflammation using febuxostat film: in vitro - in vivo correlation

Management of intraocular pressure and inflammation using febuxostat film: in vitro - in vivo correlation

Background and purpose: Urate crystal accumulation may lead to the condition of ocular tophaceous gout, causing ocular inflammation and increased intraocular pressure (IOP) due to the triggering of several inflammatory receptors like NLRP3, A2A, and TLR4. The study has been undertaken to manage int...

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Bibliographic Details
Main Authors: Mouli Das, Sk Habibullah, Tanisha Das, Rakesh Swain, Subrata Mallick
Format: Article
Language:English
Published: International Association of Physical Chemists (IAPC) 2025-01-01
Series:ADMET and DMPK
Subjects:
Anti-inflammation
Febuxostat
Hydrogel film
Intraocular pressure
in-vitro-in-vivo-correlation
Online Access:https://pub.iapchem.org/ojs/index.php/admet/article/view/2601
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