PCSK9 promotes T helper 1 and T helper 17 cell differentiation by activating the nuclear factor‐κB pathway in ankylosing spondylitis

PCSK9 promotes T helper 1 and T helper 17 cell differentiation by activating the nuclear factor‐κB pathway in ankylosing spondylitis

Abstract Objective Our previous study reveals that proprotein convertase subtilisin/kexin type 9 (PCSK9) is positively related to inflammatory markers, T helper (Th)‐17 cells, and treatment response in ankylosing spondylitis (AS) patients. Subsequently, this study aimed to explore the effect of PCSK...

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Bibliographic Details
Main Authors: Jianfei Cai, Yinghui Jiang, Fucai Chen, Shubin Wu, Hongjun Ren, Pingping Wang, Jiayong Wang, Wei Liu
Format: Article
Language:English
Published: Wiley 2023-05-01
Series:Immunity, Inflammation and Disease
Subjects:
ankylosing spondylitis
nuclear factor‐κB pathway
proprotein convertase subtilisin/kexin type 9
T helper 1 cells
T helper 17 cells
Online Access:https://doi.org/10.1002/iid3.870
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https://doi.org/10.1002/iid3.870

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