Chromatin structure and gene transcription of recombinant p53 adenovirus vector within host

IntroductionThe recombinant human p53 adenovirus (Ad-p53) offers a promising approach for cancer therapy, yet its chromatin structure and effects on host chromatin organization and gene expression are not fully understood.MethodsIn this study, we employed in situ ChIA-PET to investigate the colorect...

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Bibliographic Details
Main Authors: Duo Ning, Yuqing Deng, Simon Zhongyuan Tian
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Molecular Biosciences
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Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2025.1562357/full
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