Increasing experience in the use of papaya for burn injuries in an African context, potential and limitations
World-wide, burns are most common in low resource settings (LRS) with high mortality. Human resources, equipment and affordable, effective and safe treatments all influence outcome. Treatment of full thickness burns is particularly challenging and associated with high risk of complications. The pres...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | Burns Open |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2468912224000737 |
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| author | Helena W.C. Hofland Edris W. Kalanzi Emmie Viyuyi Tilinde Chokotho Titus M. Opegu Eduard E. Zijlstra |
| author_facet | Helena W.C. Hofland Edris W. Kalanzi Emmie Viyuyi Tilinde Chokotho Titus M. Opegu Eduard E. Zijlstra |
| author_sort | Helena W.C. Hofland |
| collection | DOAJ |
| description | World-wide, burns are most common in low resource settings (LRS) with high mortality. Human resources, equipment and affordable, effective and safe treatments all influence outcome. Treatment of full thickness burns is particularly challenging and associated with high risk of complications. The presence of an eschar, infection and hypergranulation are important factors that delay wound closure. Tropical fruits are used for treatment of wounds and burns with excellent results. These fruits are usually available throughout the year and essentially inexpensive. The efficacy of papaya and pineapple is based on enzymes that have proteolytic activity and other compounds that have antimicrobial action. In the context of reverse technology, this enzymatic therapy has formed the basis of Nexobrid™ (based on enzymes derived from pineapple) that is now standard of care in high income countries. However, it is painful and very expensive. In LRS the use of papaya paste seems an alternative attractive option; however, evidence-based studies are needed on efficacy, safety, including standardization of the product used and treatment regimens. |
| format | Article |
| id | doaj-art-c09de4e4226d4e849b0d28210aaf5842 |
| institution | Kabale University |
| issn | 2468-9122 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Burns Open |
| spelling | doaj-art-c09de4e4226d4e849b0d28210aaf58422025-01-19T06:26:26ZengElsevierBurns Open2468-91222025-01-019100385Increasing experience in the use of papaya for burn injuries in an African context, potential and limitationsHelena W.C. Hofland0Edris W. Kalanzi1Emmie Viyuyi2Tilinde Chokotho3Titus M. Opegu4Eduard E. Zijlstra5Maasstadziekenhuis, Rotterdam, the Netherlands; Rotterdam Center for Tropical Medicine, Rotterdam, the NetherlandsBurn and Plastic Surgery Department, Kiruddu Hospital, Kampala, UgandaBurn Unit, Queen Elizabeth Central Hospital, Blantyre, MalawiBurn Unit, Queen Elizabeth Central Hospital, Blantyre, MalawiMidas Touch Medical Services, Kumi, UgandaRotterdam Center for Tropical Medicine, Rotterdam, the Netherlands; Corresponding author at: Bovenstraat 21, Rotterdam Center for Tropical Medicine, The Netherlands.World-wide, burns are most common in low resource settings (LRS) with high mortality. Human resources, equipment and affordable, effective and safe treatments all influence outcome. Treatment of full thickness burns is particularly challenging and associated with high risk of complications. The presence of an eschar, infection and hypergranulation are important factors that delay wound closure. Tropical fruits are used for treatment of wounds and burns with excellent results. These fruits are usually available throughout the year and essentially inexpensive. The efficacy of papaya and pineapple is based on enzymes that have proteolytic activity and other compounds that have antimicrobial action. In the context of reverse technology, this enzymatic therapy has formed the basis of Nexobrid™ (based on enzymes derived from pineapple) that is now standard of care in high income countries. However, it is painful and very expensive. In LRS the use of papaya paste seems an alternative attractive option; however, evidence-based studies are needed on efficacy, safety, including standardization of the product used and treatment regimens.http://www.sciencedirect.com/science/article/pii/S2468912224000737Burn injuriesTreatmentPapayaAfrica |
| spellingShingle | Helena W.C. Hofland Edris W. Kalanzi Emmie Viyuyi Tilinde Chokotho Titus M. Opegu Eduard E. Zijlstra Increasing experience in the use of papaya for burn injuries in an African context, potential and limitations Burns Open Burn injuries Treatment Papaya Africa |
| title | Increasing experience in the use of papaya for burn injuries in an African context, potential and limitations |
| title_full | Increasing experience in the use of papaya for burn injuries in an African context, potential and limitations |
| title_fullStr | Increasing experience in the use of papaya for burn injuries in an African context, potential and limitations |
| title_full_unstemmed | Increasing experience in the use of papaya for burn injuries in an African context, potential and limitations |
| title_short | Increasing experience in the use of papaya for burn injuries in an African context, potential and limitations |
| title_sort | increasing experience in the use of papaya for burn injuries in an african context potential and limitations |
| topic | Burn injuries Treatment Papaya Africa |
| url | http://www.sciencedirect.com/science/article/pii/S2468912224000737 |
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