Antigen-Specific IFN-γ Responses Correlate with the Activity of M. tuberculosis Infection but Are Not Associated with the Severity of Tuberculosis Disease

Antigen-Specific IFN-γ Responses Correlate with the Activity of M. tuberculosis Infection but Are Not Associated with the Severity of Tuberculosis Disease

IFN-γ is a key cytokine in antituberculosis (TB) defense. However, how the levels of its secretion affect M. tuberculosis (Mtb) infection is not clear. We have analyzed associations between IFN-γ responses measured in QuantiFERON®-TB Gold In-tube (QFT) assay, TB disease severity, and Mtb infection a...

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Main Authors: Irina Yu. Nikitina, Alexander V. Panteleev, Ekaterina V. Sosunova, Natalya L. Karpina, Tatef R. Bagdasarian, Irina A. Burmistrova, Sofia N. Andreevskaya, Larisa N. Chernousova, Irina A. Vasilyeva, Irina V. Lyadova
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2016/7249369
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http://dx.doi.org/10.1155/2016/7249369

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