High‐Frequency Mutations in TP53, AXIN1, CTNNB1, and KRAS, and Polymorphisms in JAK1 Genes Among Mongolian HCC Patients

High‐Frequency Mutations in TP53, AXIN1, CTNNB1, and KRAS, and Polymorphisms in JAK1 Genes Among Mongolian HCC Patients

ABSTRACT Background Mongolia has the highest incidence of liver cancer worldwide, largely driven by a high prevalence of hepatitis virus infections. Mutations in oncogenes and tumor suppressor genes provide valuable insights into the molecular mechanisms of hepatocellular carcinoma (HCC). Aims This...

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Main Authors: Nomin Bold, Khurelsukh Buyanbat, Ariya Enkhtuya, Nomin Myagmar, Gerelsuren Batbayar, Zolzaya Sandag, Dolgion Damdinbazar, Nomuun Oyunbat, Tuul Boldbaatar, Ankhbayar Enkhbaatar, Gan‐Erdene Baatarjav, Taivan Nanzaddorj, Tsendsuren Oyunsuren, Gantulga Davaakhuu
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Cancer Reports
Subjects:
hepatocellular carcinoma
liver cancer
mutation
p53
β‐catenin
Online Access:https://doi.org/10.1002/cnr2.70227
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