Sarbecovirus RBD indels and specific residues dictating multi-species ACE2 adaptiveness

Sarbecovirus RBD indels and specific residues dictating multi-species ACE2 adaptiveness

Abstract Our comprehensive understanding of the multi-species ACE2 adaptiveness of sarbecoviruses remains elusive, particularly for those with various receptor binding motif (RBM) insertions/deletions (indels). Here, we analyzed RBM sequences from 268 sarbecoviruses categorized into four RBM indel t...

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Main Authors: Jun-Yu Si, Yuan-Mei Chen, Ye-Hui Sun, Meng-Xue Gu, Mei-Ling Huang, Lu-Lu Shi, Xiao Yu, Xiao Yang, Qing Xiong, Cheng-Bao Ma, Peng Liu, Zheng-Li Shi, Huan Yan
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-53029-3
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https://doi.org/10.1038/s41467-024-53029-3

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