Distinct clusters of bacterial and fungal microbiota in end-stage liver cirrhosis correlate with antibiotic treatment, intestinal barrier impairment, and systemic inflammation

Distinct clusters of bacterial and fungal microbiota in end-stage liver cirrhosis correlate with antibiotic treatment, intestinal barrier impairment, and systemic inflammation

Decompensated liver cirrhosis (dLC) is associated with intestinal dysbiosis, however, underlying reasons and clinical consequences remain largely unexplored. We investigated bacterial and fungal microbiota, their relation with gut barrier integrity, inflammation, and cirrhosis-specific complications...

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Main Authors: Laura Buttler, David A. Velázquez-Ramírez, Anja Tiede, Anna M. Conradi, Sabrina Woltemate, Robert Geffers, Birgit Bremer, Vera Spielmann, Julia Kahlhöfer, Anke R.M Kraft, Dirk Schlüter, Heiner Wedemeyer, Markus Cornberg, Christine Falk, Marius Vital, Benjamin Maasoumy
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Gut Microbes
Subjects:
Intestinal microbiome
fungi
dysbiosis
liver cirrhosis
metagenomics
gut barrier
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2025.2487209
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https://www.tandfonline.com/doi/10.1080/19490976.2025.2487209

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