MiR-125b-5p ameliorates ox-LDL-induced vascular endothelial cell dysfunction by negatively regulating TNFSF4/TLR4/NF-κB signaling

MiR-125b-5p ameliorates ox-LDL-induced vascular endothelial cell dysfunction by negatively regulating TNFSF4/TLR4/NF-κB signaling

Abstract Background Oxidized low-density lipoprotein (ox-LDL)-induced endothelial cell dysfunction plays a crucial role in the progression of atherosclerosis (AS). Although miR-125b-5p is known to be involved in cardiovascular and cerebrovascular disorders, its function in ox-LDL-induced endothelial...

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Bibliographic Details
Main Authors: Wenshuai He, Limin Zhao, Pengfei Wang, Maojia Ren, Yunfei Han
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Biotechnology
Subjects:
Atherosclerosis
HUVECs
miR-125b-5p
TNFSF4
TLR4/NF-κB signaling
Online Access:https://doi.org/10.1186/s12896-025-00944-y
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https://doi.org/10.1186/s12896-025-00944-y

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