NEDD4 family E3 ligases in osteoporosis: mechanisms and emerging potential therapeutic targets

Abstract Osteoporosis is a systemic skeletal disorder characterized by reduced bone density and an increased risk of fractures, particularly prevalent in the aging population. Osteoporotic complications, including vertebral compression fractures, hip fractures, and distal forearm fractures, affect o...

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Bibliographic Details
Main Authors: Heng Wu, Junhui Zuo, Yu Dai, Hairui Li, Song Wang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-025-05517-5
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