Factors Associated with PMTCT Cascade Completion in Four African Countries
Background. Many countries are working to reduce or eliminate mother-to-child transmission (MTCT) of HIV. Prevention efforts have been conceptualized as steps in a cascade but cascade completion rates during and after pregnancy are low. Methods. A cross-sectional survey was performed across 26 commu...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | AIDS Research and Treatment |
| Online Access: | http://dx.doi.org/10.1155/2016/2403936 |
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| author | Jodie Dionne-Odom Thomas K. Welty Andrew O. Westfall Benjamin H. Chi Didier Koumavi Ekouevi Margaret Kasaro Pius M. Tih Alan T. N. Tita |
| author_facet | Jodie Dionne-Odom Thomas K. Welty Andrew O. Westfall Benjamin H. Chi Didier Koumavi Ekouevi Margaret Kasaro Pius M. Tih Alan T. N. Tita |
| author_sort | Jodie Dionne-Odom |
| collection | DOAJ |
| description | Background. Many countries are working to reduce or eliminate mother-to-child transmission (MTCT) of HIV. Prevention efforts have been conceptualized as steps in a cascade but cascade completion rates during and after pregnancy are low. Methods. A cross-sectional survey was performed across 26 communities in Cameroon, Cote d’Ivoire, South Africa, and Zambia. Women who reported a pregnancy within two years were enrolled. Participant responses were used to construct the PMTCT cascade with all of the following steps required for completion: at least one antenatal visit, HIV testing performed, HIV testing result received, initiation of maternal prophylaxis, and initiation of infant prophylaxis. Factors associated with cascade completion were identified using multivariable logistic regression modeling. Results. Of 976 HIV-infected women, only 355 (36.4%) completed the PMTCT cascade. Although most women (69.2%) did not know their partner’s HIV status; awareness of partner HIV status was associated with cascade completion (aOR 1.4, 95% CI 1.01–2.0). Completion was also associated with receiving an HIV diagnosis prior to pregnancy compared with HIV diagnosis during or after pregnancy (aOR 14.1, 95% CI 5.2–38.6). Conclusions. Pregnant women with HIV infection in Africa who were aware of their partner’s HIV status and who were diagnosed with HIV before pregnancy were more likely to complete the PMTCT cascade. |
| format | Article |
| id | doaj-art-bfbbce52a7b044c08a0d716e8389a215 |
| institution | Kabale University |
| issn | 2090-1240 2090-1259 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | AIDS Research and Treatment |
| spelling | doaj-art-bfbbce52a7b044c08a0d716e8389a2152025-02-03T06:08:22ZengWileyAIDS Research and Treatment2090-12402090-12592016-01-01201610.1155/2016/24039362403936Factors Associated with PMTCT Cascade Completion in Four African CountriesJodie Dionne-Odom0Thomas K. Welty1Andrew O. Westfall2Benjamin H. Chi3Didier Koumavi Ekouevi4Margaret Kasaro5Pius M. Tih6Alan T. N. Tita7University of Alabama at Birmingham, Birmingham, AL, USACameroon Baptist Convention Health Services (CBCHS), Bamenda, CameroonUniversity of Alabama at Birmingham, Birmingham, AL, USAUniversity of North Carolina at Chapel Hill, Chapel Hill, NC, USAResearch Center INSERM U1219, ISPED, Université de Bordeaux, Bordeaux, FranceUniversity of North Carolina at Chapel Hill, Chapel Hill, NC, USACameroon Baptist Convention Health Services (CBCHS), Bamenda, CameroonUniversity of Alabama at Birmingham, Birmingham, AL, USABackground. Many countries are working to reduce or eliminate mother-to-child transmission (MTCT) of HIV. Prevention efforts have been conceptualized as steps in a cascade but cascade completion rates during and after pregnancy are low. Methods. A cross-sectional survey was performed across 26 communities in Cameroon, Cote d’Ivoire, South Africa, and Zambia. Women who reported a pregnancy within two years were enrolled. Participant responses were used to construct the PMTCT cascade with all of the following steps required for completion: at least one antenatal visit, HIV testing performed, HIV testing result received, initiation of maternal prophylaxis, and initiation of infant prophylaxis. Factors associated with cascade completion were identified using multivariable logistic regression modeling. Results. Of 976 HIV-infected women, only 355 (36.4%) completed the PMTCT cascade. Although most women (69.2%) did not know their partner’s HIV status; awareness of partner HIV status was associated with cascade completion (aOR 1.4, 95% CI 1.01–2.0). Completion was also associated with receiving an HIV diagnosis prior to pregnancy compared with HIV diagnosis during or after pregnancy (aOR 14.1, 95% CI 5.2–38.6). Conclusions. Pregnant women with HIV infection in Africa who were aware of their partner’s HIV status and who were diagnosed with HIV before pregnancy were more likely to complete the PMTCT cascade.http://dx.doi.org/10.1155/2016/2403936 |
| spellingShingle | Jodie Dionne-Odom Thomas K. Welty Andrew O. Westfall Benjamin H. Chi Didier Koumavi Ekouevi Margaret Kasaro Pius M. Tih Alan T. N. Tita Factors Associated with PMTCT Cascade Completion in Four African Countries AIDS Research and Treatment |
| title | Factors Associated with PMTCT Cascade Completion in Four African Countries |
| title_full | Factors Associated with PMTCT Cascade Completion in Four African Countries |
| title_fullStr | Factors Associated with PMTCT Cascade Completion in Four African Countries |
| title_full_unstemmed | Factors Associated with PMTCT Cascade Completion in Four African Countries |
| title_short | Factors Associated with PMTCT Cascade Completion in Four African Countries |
| title_sort | factors associated with pmtct cascade completion in four african countries |
| url | http://dx.doi.org/10.1155/2016/2403936 |
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