MHC Class I Molecules Exacerbate Viral Infection by Disrupting Type I Interferon Signaling

MHC class I molecules are key in the presentation of antigen and initiation of adaptive CD8+ T cell responses. In addition to its classical activity, MHC I may possess nonclassical functions. We have previously identified a regulatory role of MHC I in TLR signaling and antibacterial immunity. Howeve...

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Bibliographic Details
Main Authors: Simo Xia, Yijie Tao, Likun Cui, Yizhi Yu, Sheng Xu
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2019/5370706
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