MHC Class I Molecules Exacerbate Viral Infection by Disrupting Type I Interferon Signaling
MHC class I molecules are key in the presentation of antigen and initiation of adaptive CD8+ T cell responses. In addition to its classical activity, MHC I may possess nonclassical functions. We have previously identified a regulatory role of MHC I in TLR signaling and antibacterial immunity. Howeve...
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Main Authors: | Simo Xia, Yijie Tao, Likun Cui, Yizhi Yu, Sheng Xu |
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Format: | Article |
Language: | English |
Published: |
Wiley
2019-01-01
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Series: | Journal of Immunology Research |
Online Access: | http://dx.doi.org/10.1155/2019/5370706 |
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