Cellular EMT-status governs contact guidance in an electrospun TACS-mimicking in vitro model

In this study, an advanced nanofiber breast cancer in vitro model was developed and systematically characterized including physico-chemical, cell-biological and biophysical parameters. Using electrospinning, the architecture of tumor-associated collagen signatures (TACS5 and TACS6) was mimicked. By...

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Bibliographic Details
Main Authors: Lorenz Isert, Mehak Passi, Benedikt Freystetter, Maximilian Grab, Andreas Roidl, Christoph Müller, Aditi Mehta, Harini G. Sundararaghavan, Stefan Zahler, Olivia M. Merkel
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Materials Today Bio
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006424004629
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