NaHS alleviates neuropathic pain in mice by inhibiting IL-17-mediated dopamine (DA) neuron necroptosis in the VTA

NaHS alleviates neuropathic pain in mice by inhibiting IL-17-mediated dopamine (DA) neuron necroptosis in the VTA

Background: Neuropathic pain (NP) constitutes a significant burden for individuals, manifesting as nociceptive anaphylaxis, hypersensitivity, and spontaneous pain. Previous research has suggested that the analgesic effects of NP are mediated by dopamine (DA) neurons in the ventral tegmental region (...

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Bibliographic Details
Main Authors: Jun Wang, Nan Zhang, Hong-Zheng Liu, Jin-Liang Wang, Yong-Bo Zhang, Dong-Dong Su, Li-Min Zhang, Bao-Dong Li, Hui-Tao Miao, Jun Miao
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Brain Research Bulletin
Subjects:
Neuropathic pain
H2S
Necroptosis
Dopamine (DA) neurons
IL-17
Online Access:http://www.sciencedirect.com/science/article/pii/S0361923024003022
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