Play-the-winner rule and adaptive designs of clinical trials

In another paper, we have argued that the traditional randomized design of clinical trials is ethically infeasible in desperate medical situations and adaptive designs are morally required. We have also argued that in such situations, the appropriate designs must satisfy what we call the Principle o...

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Bibliographic Details
Main Authors: Xikui Wang, Daryl Pullman
Format: Article
Language:English
Published: Wiley 2001-01-01
Series:International Journal of Mathematics and Mathematical Sciences
Online Access:http://dx.doi.org/10.1155/S0161171201005750
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