Intra-serotype variation of Streptococcus pneumoniae capsule and its quantification

Intra-serotype variation of Streptococcus pneumoniae capsule and its quantification

ABSTRACT Streptococcus pneumoniae (Spn) is a leading respiratory pathogen that depends on a thick layer of capsular polysaccharide (CPS) to evade immune clearance. Disease prevention by CPS-based vaccines is limited because of the species’ high genome plasticity and ability to express over 100 diffe...

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Bibliographic Details
Main Authors: Hannes Eichner, Cindy Wu, Michael Cammer, Elizabeth N. H. Tran, Timothy R. Hirst, James C. Paton, Jeffrey N. Weiser
Format: Article
Language:English
Published: American Society for Microbiology 2025-04-01
Series:Microbiology Spectrum
Subjects:
pneumococcus
immunoblotting
polysaccharides
image analysis
capsule
confocal microscopy
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03087-24
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https://journals.asm.org/doi/10.1128/spectrum.03087-24

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