Role of hypoxia-inducible-factor-1α (HIF-1α) in ferroptosis of adipose tissue during ketosis

Role of hypoxia-inducible-factor-1α (HIF-1α) in ferroptosis of adipose tissue during ketosis

ABSTRACT: Postpartum cows experience lipolysis in adipose tissue due to negative energy balance, and accumulation of free fatty acids leads to metabolic stress in adipose tissue. Ferroptosis is a type of cell death triggered by excessive buildup of iron-dependent lipid peroxides and is involved in t...

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Bibliographic Details
Main Authors: Yunhui Fan, Li Ma, Xinxin Fang, Shuyu Du, John Mauck, Juan J. Loor, Xudong Sun, Hongdou Jia, Chuang Xu, Qiushi Xu
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Journal of Dairy Science
Subjects:
HIF-1α
bovine adipocytes
oxidative stress
ferroptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0022030224010348
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