Citronellal Exerts Sedative‐Like Effects and Augments Diazepam's Action in Swiss Mice, Possibly Through the GABAergic Pathway

Citronellal Exerts Sedative‐Like Effects and Augments Diazepam's Action in Swiss Mice, Possibly Through the GABAergic Pathway

ABSTRACT Introduction Citronellal (CTL), a monoterpenoid, exhibits notable neurological activity, including anxiolytic, and anticonvulsant effects, primarily through GABAergic pathways. Our current study aimed to explore CTL's sedative potential using in vitro, in vivo, and in silico approaches...

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Bibliographic Details
Main Authors: Md. Torequl Islam, Md. Sakib Al Hasan, Emon Mia, Irfan Aamer Ansari, Siddique Akber Ansari, Md. Amirul Islam, Md. Saifuzzaman
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Brain and Behavior
Subjects:
citronellal
GABAkine pathway
monoterpene aldehyde
sedative effect
Online Access:https://doi.org/10.1002/brb3.70446
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https://doi.org/10.1002/brb3.70446

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