Application of dental pulp stem cell-conditioned medium combined with deep cryopreservation of autologous cranial flaps

Application of dental pulp stem cell-conditioned medium combined with deep cryopreservation of autologous cranial flaps

Abstract Background Autologous cranial flaps preservation after decompressive craniectomy (DC) is crucial for cranioplasty, yet standard cryopreservation carries high complication rates 15–35%, primarily infections and bone resorption. These complications frequently necessitate surgical revisions an...

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Bibliographic Details
Main Authors: Ye Liu, Yonghao Liu, Zhifei Ye, Xinxin Wang, Junyi Li, Peter L. Mei, Li Duan, Ben Wang, Chun Xu, Wei Xiong, Yan He, Qingsong Ye
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Stem Cell Research & Therapy
Subjects:
Decompressive craniectomy
Autologous cranial flaps
Deep cryopreservation
Dental pulp stem cells
Dental pulp stem cell-conditioned medium
Bone regeneration
Online Access:https://doi.org/10.1186/s13287-025-04407-1
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https://doi.org/10.1186/s13287-025-04407-1

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