Novel Compound Heterozygous Variants in ZNF526 Causing Dentici‐Novelli Neurodevelopmental Syndrome: A Case Report and Literature Review

Novel Compound Heterozygous Variants in ZNF526 Causing Dentici‐Novelli Neurodevelopmental Syndrome: A Case Report and Literature Review

ABSTRACT Background The ZNF526 gene encodes a ubiquitously expressed Kruppel‐type zinc finger protein crucial in transcriptional regulation. Recent studies suggest that biallelic pathogenic variants in ZNF526 may lead to Dentici‐Novelli neurodevelopmental syndrome, characterized by microcephaly, dev...

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Bibliographic Details
Main Authors: Shaoxin Li, Hui Fang, Hong Li, Min Peng, Jinsong Bao, Yunfei Cai, Jing Chen, Zhige Li
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
Dentici‐Novelli neurodevelopmental syndrome
global developmental delay
microcephaly
neurodevelopmental disorder
ZNF526 gene
Online Access:https://doi.org/10.1002/mgg3.70089
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https://doi.org/10.1002/mgg3.70089

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