Human guanylate binding proteins potentiate the anti-chlamydia effects of interferon-gamma.

Chlamydiae are obligate intracellular pathogens that are sensitive to pro-inflammatory cytokine interferon-gamma. IFN-gamma-inducible murine p47 GTPases have been demonstrated to function in resistance to chlamydia infection in vivo and in vitro. Because the human genome does not encode IFN-gamma-in...

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Bibliographic Details
Main Authors: Illya Tietzel, Christelle El-Haibi, Rey A Carabeo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0006499&type=printable
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