EPA-lactone derivative, 5,6-diHETE lactone, improves pulmonary arterial hypertension in a monocrotaline-induced model
BackgroundPulmonary arterial hypertension (PAH) is a progressive pulmonary arteriopathy characterized by vascular remodeling and subsequent increases in pulmonary vascular resistance, which further develops into right ventricular failure and death. Currently, PAH management targets pulmonary vasocon...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-07-01
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| Series: | Frontiers in Pharmacology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2025.1621030/full |
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