NIAID Workshop Report: Systematic Approaches for ESKAPE Bacteria Antigen Discovery

On 14–15 November 2023, the National Institute of Allergy and Infectious Diseases (NIAID) organized a workshop entitled “Systematic Approaches for ESKAPE Bacteria Antigen Discovery”. The goal of the workshop was to engage scientists from diverse relevant backgrounds to explore novel technologies tha...

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Main Authors: Inka Sastalla, Keehwan Kwon, Clayton Huntley, Kimberly Taylor, Liliana Brown, Tamika Samuel, Lanling Zou
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Vaccines
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Online Access:https://www.mdpi.com/2076-393X/13/1/87
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author Inka Sastalla
Keehwan Kwon
Clayton Huntley
Kimberly Taylor
Liliana Brown
Tamika Samuel
Lanling Zou
author_facet Inka Sastalla
Keehwan Kwon
Clayton Huntley
Kimberly Taylor
Liliana Brown
Tamika Samuel
Lanling Zou
author_sort Inka Sastalla
collection DOAJ
description On 14–15 November 2023, the National Institute of Allergy and Infectious Diseases (NIAID) organized a workshop entitled “Systematic Approaches for ESKAPE Bacteria Antigen Discovery”. The goal of the workshop was to engage scientists from diverse relevant backgrounds to explore novel technologies that can be harnessed to identify and address current roadblocks impeding advances in antigen and vaccine discoveries for the ESKAPE pathogens (<i>Enterococcus faecium</i>, <i>Staphylococcus aureus</i>, <i>Klebsiella pneumoniae</i>, <i>Acinetobacter baumannii</i>, <i>Pseudomonas aeruginosa,</i> and <i>Enterobacter</i> species). The workshop consisted of four sessions that addressed ESKAPE infections, antigen discovery and vaccine efforts, and new technologies including systems immunology and vaccinology approaches. Each session was followed by a panel discussion. In total, there were over 260 in-person and virtual attendees, with high levels of engagement. This report provides a summary of the event and highlights challenges and opportunities in the field of ESKAPE vaccine discovery.
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series Vaccines
spelling doaj-art-bd8c91a9b4d54a1d80e1b45384ab263d2025-01-24T13:51:54ZengMDPI AGVaccines2076-393X2025-01-011318710.3390/vaccines13010087NIAID Workshop Report: Systematic Approaches for ESKAPE Bacteria Antigen DiscoveryInka Sastalla0Keehwan Kwon1Clayton Huntley2Kimberly Taylor3Liliana Brown4Tamika Samuel5Lanling Zou6Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852, USADivision of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852, USADivision of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852, USADivision of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852, USADivision of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852, USADivision of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852, USADivision of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852, USAOn 14–15 November 2023, the National Institute of Allergy and Infectious Diseases (NIAID) organized a workshop entitled “Systematic Approaches for ESKAPE Bacteria Antigen Discovery”. The goal of the workshop was to engage scientists from diverse relevant backgrounds to explore novel technologies that can be harnessed to identify and address current roadblocks impeding advances in antigen and vaccine discoveries for the ESKAPE pathogens (<i>Enterococcus faecium</i>, <i>Staphylococcus aureus</i>, <i>Klebsiella pneumoniae</i>, <i>Acinetobacter baumannii</i>, <i>Pseudomonas aeruginosa,</i> and <i>Enterobacter</i> species). The workshop consisted of four sessions that addressed ESKAPE infections, antigen discovery and vaccine efforts, and new technologies including systems immunology and vaccinology approaches. Each session was followed by a panel discussion. In total, there were over 260 in-person and virtual attendees, with high levels of engagement. This report provides a summary of the event and highlights challenges and opportunities in the field of ESKAPE vaccine discovery.https://www.mdpi.com/2076-393X/13/1/87ESKAPE bacteriaantigenvaccine
spellingShingle Inka Sastalla
Keehwan Kwon
Clayton Huntley
Kimberly Taylor
Liliana Brown
Tamika Samuel
Lanling Zou
NIAID Workshop Report: Systematic Approaches for ESKAPE Bacteria Antigen Discovery
Vaccines
ESKAPE bacteria
antigen
vaccine
title NIAID Workshop Report: Systematic Approaches for ESKAPE Bacteria Antigen Discovery
title_full NIAID Workshop Report: Systematic Approaches for ESKAPE Bacteria Antigen Discovery
title_fullStr NIAID Workshop Report: Systematic Approaches for ESKAPE Bacteria Antigen Discovery
title_full_unstemmed NIAID Workshop Report: Systematic Approaches for ESKAPE Bacteria Antigen Discovery
title_short NIAID Workshop Report: Systematic Approaches for ESKAPE Bacteria Antigen Discovery
title_sort niaid workshop report systematic approaches for eskape bacteria antigen discovery
topic ESKAPE bacteria
antigen
vaccine
url https://www.mdpi.com/2076-393X/13/1/87
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