Effect of the TLR9 signaling pathway on acyclovir infection with herpes simplex virus type 2 in HaCaT cells

Effect of the TLR9 signaling pathway on acyclovir infection with herpes simplex virus type 2 in HaCaT cells

IntroductionThe objective of this study was to investigate the effect of acyclovir (ACV) on the TLR9 signaling pathway after human immortalized epidermal (HaCaT) cell infection with herpes simplex virus type 2 (HSV-2).MethodsIn this study, an in vitro cell model of HSV-2 infection was successfully c...

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Bibliographic Details
Main Authors: Jialing Shi, Lin Kuang, Li Qi, Ruoyu Li, Yangfan Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Microbiology
Subjects:
HSV-2
acyclovir
TLR9
RNA-seq
HaCaT
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1560340/full
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