A high fat, high sugar diet exacerbates persistent post-surgical pain and modifies the brain-microbiota-gut axis in adolescent rats

A high fat, high sugar diet exacerbates persistent post-surgical pain and modifies the brain-microbiota-gut axis in adolescent rats

Persistent post-surgical pain (PPSP) occurs in a proportion of patients following surgical interventions. Research suggests that specific microbiome components are important for brain development and function, with recent studies demonstrating that chronic pain results in changes to the microbiome....

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Bibliographic Details
Main Authors: Sabrina Salberg, Matthew Macowan, Angela Doshen, Glenn R. Yamakawa, Marissa Sgro, Benjamin Marsland, Luke A. Henderson, Richelle Mychasiuk
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:NeuroImage
Subjects:
MRI
16s rRNA
Diffusivity
Akkermansia
Bacteroides
Nociception
Online Access:http://www.sciencedirect.com/science/article/pii/S105381192500059X
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