Targeted treatment for neuroblastoma using methoxyestradiol (2-ME)-loaded mitochondria-targeting immunoliposomes modified by datuximab (anti-GD2) and (L-cyclohexyl alanine-D-arginine)3 ((Fx,r)3) peptide
Abstract The 2-ME therapy encounters significant challenges in practical use. Its low water solubility compromises bioavailability, limiting drug efficacy. In addition, poor stability in the physiological environment hinders sustained therapeutic effects, and insufficient targeting may harm normal t...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-06-01
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| Series: | Cancer Nanotechnology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12645-025-00335-0 |
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