Integrative Transcriptomic Profiling Identifies <i>TNF</i> and <i>IL1B</i> as Candidate Key Early-Response Genes in Macrophages Infected with Smooth <i>Brucella</i> Using a Comprehensive Bioinformatic Approach

Integrative Transcriptomic Profiling Identifies <i>TNF</i> and <i>IL1B</i> as Candidate Key Early-Response Genes in Macrophages Infected with Smooth <i>Brucella</i> Using a Comprehensive Bioinformatic Approach

Smooth <i>Brucella</i> are the main pathogenic bacteria that threaten human health and food safety. The early stage of smooth <i>Brucella</i> and macrophage interaction is an important phase, and smooth <i>Brucella</i> species elicit a dramatic transcriptional res...

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Bibliographic Details
Main Authors: Xiaoyu Yang, Qiang Chen
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Biology
Subjects:
macrophage
smooth <i>Brucella</i>
transcriptional response
key gene
bioinformatics
Online Access:https://www.mdpi.com/2079-7737/14/5/579
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