Echinococcus granulosus promotes MAPK pathway-mediated osteoclast differentiation by inhibiting Nrf2 in osseous echinococcosis
Abstract Osseous echinococcosis causes severe “osteolytic” changes in the bone tissue of Echinococcus granulosus (E. granulosus) infection sites by promoting the over-differentiation of osteoclasts at the site. Nrf2 is a key regulator of osteoclast differentiation and formation, and this study inves...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-04-01
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| Series: | Veterinary Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13567-025-01510-2 |
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