Thermostable lamprey variable lymphocyte receptor antibody for detection of Plasmodium falciparum histidine rich protein-2

Abstract Lampreys use variable lymphocyte receptors (VLR) comprising leucine-rich-repeat (LRR) segments for antigen recognition, distinct from immunoglobulin-based receptors of jawed vertebrates. Lamprey VLRs are as diverse and antigen-specific as immunoglobulin-based antibodies, with unique advanta...

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Bibliographic Details
Main Authors: Deepak Tomar, Balwan Singh, Masayuki Hirano, Samadhi Senanayake, Michael Aidoo, Eric Rogier, Oskar Laur, Brantley R. Herrin, Venkatachalam Udhayakumar
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-97790-x
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