Brain-wide microstrokes affect the stability of memory circuits in the hippocampus

Abstract Cognitive deficits affect over 70% of stroke survivors, yet the mechanisms by which multiple small ischemic events contribute to cognitive decline remain poorly understood. In this study, we employed chronic two-photon calcium imaging to longitudinally track the fate of individual neurons i...

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Bibliographic Details
Main Authors: Hendrik Heiser, Filippo Kiessler, Adrian Roggenbach, Victor Ibanez, Martin Wieckhorst, Fritjof Helmchen, Julijana Gjorgjieva, Anna-Sophia Wahl
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58688-4
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