Extracellular Vesicles as Tools for Crossing the Blood–Brain Barrier to Treat Lysosomal Storage Diseases

Extracellular Vesicles as Tools for Crossing the Blood–Brain Barrier to Treat Lysosomal Storage Diseases

Extracellular vesicles (EVs) are nanosized, membrane-bound structures that have emerged as promising tools for drug delivery, especially in the treatment of lysosomal storage disorders (LSDs) with central nervous system (CNS) involvement. This review highlights the unique properties of EVs, such as...

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Bibliographic Details
Main Authors: Giovanni Lerussi, Verónica Villagrasa-Araya, Marc Moltó-Abad, Mireia del Toro, Guillem Pintos-Morell, Joaquin Seras-Franzoso, Ibane Abasolo
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Life
Subjects:
blood–brain barrier
drug delivery
enzyme replacement therapy
exosomes
extracellular vesicles
lysosomal storage diseases
Online Access:https://www.mdpi.com/2075-1729/15/1/70
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