Ubiquitin-specific protease 25 ameliorates ulcerative colitis by regulating the degradation of phosphor-STAT3

Abstract Ubiquitin-specific protease 25 (USP25), a member of the deubiquitination family, plays an important role in protein ubiquitination, degradation, inflammation, and immune regulation. However, the role and mechanism of USP25 in ulcerative colitis (UC) remain unclear. To study the role and mec...

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Bibliographic Details
Main Authors: Zhengru Liu, Jian Liu, Yuping Wei, Jinting Li, Jixiang Zhang, Rong Yu, Qian Yang, Yinglei Miao, Weiguo Dong
Format: Article
Language:English
Published: Nature Publishing Group 2025-01-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-07315-z
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